Results 241 to 250 of about 4,844,764 (298)

Cardiac Arrest Survivors' Perspectives to Inform the Co-Design of a Web-Based Support and Learning Platform: Qualitative Content Analysis. [PDF]

J Med Internet Res
Waldemar A, Bremer A, Israelsson J, Heimburg K, Nordberg P, Blennow Nordström E, Årestedt K, Thylén I, Thylén I.   +8 more
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Evaluating the quality and reliability of pulmonary embolism-related short videos on Bilibili and TikTok: A cross-sectional content analysis. [PDF]

Medicine (Baltimore)
Lv W, Wang L, Wu M, Zhu M.
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Mapping the complexity of psychomotor skills in core nursing procedures: A content analysis for simulation-based education. [PDF]

Int J Nurs Stud Adv
Kim H, Koh A, Lee S, Jin S, Hyun MH, Shin H.   +5 more
europepmc   +1 more source

Patients' Perspective of Medication Safety in Hungary: A Netnography-Based Mixed-Method Content Analysis. [PDF]

Healthcare (Basel)
Báldy B, Lám J.
europepmc   +1 more source

Integration of Social Media to Enhance Engagement With a Medical Education Website: A Content Analysis. [PDF]

Cureus
Sidhoo SK, Dou A, Patel V, Zhang J, Sun D, Ingledew PA.   +5 more
europepmc   +1 more source

Linguistic diversity in machine learning training data: Content analysis of English and Finnish soundscape descriptions in audio captioning. [PDF]

PLoS One
Hekanaho L, Tuuri E, Surakka M, Hirvonen M.   +3 more
europepmc   +1 more source

Exploring the Role of Midwives in Promoting Childbearing from the Perspective of Couples: A Qualitative Content Analysis. [PDF]

Int J Community Based Nurs Midwifery
Esfandiarinezhad P, Javadifar N, Iravani M.   +2 more
europepmc   +1 more source