Results 51 to 60 of about 227,300 (265)

A Hybrid Content-Based and Collaborative Filtering Approach for Recommending Optimal Movie Release Months

open access: yesJournal of Applied Informatics and Computing
The film industry faces increasingly intense competition, making release timing a critical factor in maximizing box-office performance. However, decisions regarding release months are often driven by producers’ intuition rather than systematic data ...
Ukasyah Muntaha   +5 more
doaj   +1 more source

Comparison Between Collaborative Filtering and Content-Based Filtering

open access: yesHighlights in Science, Engineering and Technology, 2022
With the rapid development of Internet technology nowadays, how to quickly obtain the effective information needed by users has become the key point of the scientific and technological academia. Therefore, various kinds of recommendation algorithms have been invented. Based on the previous research, this paper introduces the most famous and widely used
openaire   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

A Recommendation System Based on Fuzzy Signature

open access: yesIEEE Access
In recent years, recommendation systems have become essential tools for managing the overwhelming volume of information users face daily. In the context of Technology Enhanced Learning (TEL), for instance, where learners can be faced with a large variety
Giuseppe D'Aniello   +2 more
doaj   +1 more source

Forward a hybrid AI fashion recommender system blending trends and personal style based on fuzzy systems [PDF]

open access: yesPeerJ Computer Science
During recent years, the accelerated evolution of online fashion trends and seasonal dynamics has increased the demand for intelligent recommendation systems capable of balancing personalization and novelty.
Aladdin Masri, Muhannad Al-Jabi
doaj   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Pekalongan Regency Tourism Recommendation System with Content based Filtering

open access: yesSistemasi: Jurnal Sistem Informasi
This study implements content-based filtering for a tourist recommendation system in Pekalongan Regency. The method utilizes the TF-IDF algorithm to measure the weight of tourist attraction categories and cosine similarity to assess the similarity ...
Cinta Salsabilla, Danang Wahyu Utomo
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

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