Results 61 to 70 of about 227,300 (265)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Hybrid-Based Movie Recommender System: Techniques, Case Studies, Evaluation Metrics, and Future Trends

open access: yesJournal of Informatics and Web Engineering
The necessity for sophisticated recommender systems in the movie recommendation sphere has become particularly pronounced, generating a more personalized movie recommendation due to people nowadays who like to watch movies online.
Cheng-Yung Lai   +2 more
doaj   +3 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Hybrid Approach for a Knowledge Recommender Service: A Combination of Item-Based and Tag-Based Recommendation

open access: yesWalailak Journal of Science and Technology, 2017
An exponentially increasing of knowledge in a knowledge management system is the main cause of the knowledge overload problem. A development of knowledge recommender service embedded in the knowledge management system becomes a challenging task.
Winyu NIRANATLAMPHONG   +1 more
doaj  

ANALYSIS OF CONTENT RECOMMENDATION METHODS IN INFORMATION SERVICES

open access: yesInformatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska
The object of the research is the process of selecting a content recommendation method in information services. The study's relevance stems from the rapid development of informational and entertainment resources and the increasing volume of data they ...
Oleksandr Necheporuk   +4 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Hybrid Collaborative Filtering and Content-Based Filtering for Improved Recommender System [PDF]

open access: yes, 2004
The growth of the Internet has resulted in an increasing need for personalized information systems. The paper describes an autonomous agent, WebBot: Web Robot Agent, which integrates with the web and acts as a personal recommender system that cooperates with the user on identifying interesting pages.
Kyung-Yong Jung   +2 more
openaire   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

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