Results 61 to 70 of about 687,174 (294)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A systematic review and research perspective on recommender systems

open access: yesJournal of Big Data, 2022
Recommender systems are efficient tools for filtering online information, which is widespread owing to the changing habits of computer users, personalization trends, and emerging access to the internet.
Deepjyoti Roy, Mala Dutta
doaj   +1 more source

Apparel Recommendation System using Content-Based Filtering

open access: yesInternational Journal of Recent Technology and Engineering (IJRTE), 2022
Nowadays, people are constantly moving towards various fashion products as a result the e-commerce market for garments is growing rapidly. Online stores must update their features according to user requirements and preferences. However, there are too many options for users to select from these online stores which may leave them in a dilemma to identify
Sagar Yeruva   +4 more
openaire   +1 more source

An evaluation of the role of sentiment in second screen microblog search tasks [PDF]

open access: yes, 2012
The recent prominence of the real-time web is proving both challenging and disruptive for information retrieval and web data mining research. User-generated content on the real-time web is perhaps best epitomised by content on microblogging platforms ...
Bermingham, Adam, Smeaton, Alan F.
core  

Content-Based Weak Supervision for Ad-Hoc Re-Ranking

open access: yes, 2019
One challenge with neural ranking is the need for a large amount of manually-labeled relevance judgments for training. In contrast with prior work, we examine the use of weak supervision sources for training that yield pseudo query-document pairs that ...
Dietz Laura   +4 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Systematic Literature Review on Recommender System: Approach, Problem, Evaluation Techniques, Datasets

open access: yesIEEE Access
Recommender systems become essential with the presence of the internet and social media. The perceived benefits of the recommender system can make it easier for users to find suitable products and recommend other products, specifically with lots of ...
Ilham Saifudin, Triyanna Widiyaningtyas
doaj   +1 more source

Preference Networks: Probabilistic Models for Recommendation Systems [PDF]

open access: yes, 2014
Recommender systems are important to help users select relevant and personalised information over massive amounts of data available. We propose an unified framework called Preference Network (PN) that jointly models various types of domain knowledge for ...
Phung, Dinh Q.   +2 more
core   +1 more source

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