Results 41 to 50 of about 1,789,288 (264)

Secure and Efficient Content Distribution in Crowdsourced Vehicular Content-Centric Networking

open access: yesIEEE Access, 2018
In future intelligent transportation systems, a large amount of content needs to be efficiently and securely exchanged between vehicles and roadside units via vehicular networks to improve the driving and traveling experience.
Chengming Li   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Camptothecin Distribution and Content in

open access: yesNatural Product Communications, 2011
Nothapodytes nimmoniana is an important anticancer medicinal plant which possesses various bioactive substances, of which camptothecin (CPT) is the most important. CPT is mainly obtained by extraction from plants.
Ao Mingzhang   +4 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Ethical requirements for generative AI in brand content creation: a qualitative comparative analysis

open access: yesFrontiers in Communication
With the rapid integration of Generative AI (GenAI) for brand content creation in content marketing, clearer guidelines for responsible adoption have become important.
Charmaine Du Plessis
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Design and optimization of Content Distribution Networks

open access: yesТруды Института системного программирования РАН, 2019
This article presents the application of soft computing methods for solving the problem of designing and optimizing cloud-based Content Distribution Networks (CDN).
Santiago Damian Iturriaga Fabra   +4 more
doaj   +1 more source

Privacy in Content Distribution Networks [PDF]

open access: yes, 2003
A framework is proposed for secure delivery of personalized content in the presence of a transparent intermediary while the privacy of the user is being preserved. The framework includes delegation of authority to the intermediary content distributor allowing him to act on behalf of the content provider. To maximize privacy, the framework enables users
openaire   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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