Results 51 to 60 of about 1,789,288 (264)

Content investigation and reason analysis of zerocited supported articles in clinical nursing field published in nursing core periodical

open access: yesHuli yanjiu, 2018
Objective:To analyze the reasons of zerocited fund paper in the clinical nursing field published in nursing core periodical in China,find out the problems in the course of nursing research,and to provide a reference for nursing staff picking topics and
程金莲   +4 more
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Heuristic Approach to Determining Cache Node Locations in Content-Centric Networks

open access: yesIEEE Access, 2018
Internet users consider content information to be useful, but the current Internet approach treats location information as more important as so ties the former to the latter.
Nattapong Kitsuwan   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

An Efficient Content Distribution Network Architecture Using Heterogeneous Channels

open access: yesIEEE Access, 2020
With the popularization and development of the IoT(Internet of Things), more and more data needs to be transmitted over the Internet, which leads to the deterioration of network quality.
Yuqiang Wen   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Analysis of digital marketing and its effect on the positioning of Peruvian universities in 2023 - Análisis del marketing digital y su efecto en el posicionamiento de las universidades peruanas en 2023

open access: yesSuma de Negocios
: Introduction/Objective: Any change and strategic advertising and/or commercial planning carried out by means of digital media is called digital marketing, which helps universities to position themselves, which is why Peruvian universities create and ...
Yilda Lisset Canaza Calsina   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Location-assistant content distribution scheme for emergency rescue

open access: yesInternational Journal of Distributed Sensor Networks, 2018
In order to optimize the timeliness and pertinence of message delivery in emergency rescue scenarios and improve the service performance of emergency communications network, we propose a location-assistant content distribution scheme based on delay ...
Guomin Zhang   +4 more
doaj   +1 more source

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