Results 41 to 50 of about 1,230,989 (267)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Nanoscale Morphology, Interfacial Hydrogen Bonding, Confined Crystallization and Greatly Improved Toughness of Polyamide 12/Polyketone Blends

open access: yesNanomaterials, 2018
Nanostructured polyamide 12(PA12)/polyketone (PK) blends were fabricated by melt compounding. The nanoscale droplet and domain-in-domain morphologies depending on PK content were observed.
Siyuan Li   +5 more
doaj   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Defining Roles in Pediatric Palliative Care: Perspectives From Oncology and Palliative Care Teams

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Early integration of pediatric palliative care (PPC) is associated with improved symptom management, quality of life, and healthcare utilization for children with cancer. Despite this, variation persists in how PPC is understood, operationalized, and integrated within pediatric oncology programs. In particular, ambiguity surrounding
Leeat Granek   +13 more
wiley   +1 more source

Feasibility and Preliminary Efficacy of Integrative Neuromuscular Training for Childhood Cancer Survivors: A Pilot Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian   +7 more
wiley   +1 more source

Multiple Moving Object Detection for Fast Video Content Description in Compressed Domain

open access: yesEURASIP Journal on Advances in Signal Processing, 2007
Indexing deals with the automatic extraction of information with the objective of automatically describing and organizing the content. Thinking of a video stream, different types of information can be considered semantically important.
Boris Mansencal   +3 more
doaj   +1 more source

Modelling Subject Domain Causality for Learning Content Renewal

open access: yesInformatica, 2019
The paper deals with the causality driven modelling method applied for the domain deep knowledge elicitation. This method is suitable for discovering causal relationships in domains that are characterized by internal circular causality, e.g. control and management, regulatory processes, self-regulation and renewal.
Gudas, Saulius   +3 more
openaire   +3 more sources

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

The regulation of abusive activity and content: a study of registries’ terms of service

open access: yesInternet Policy Review, 2020
This paper studies the role of domain registries in relation to unlawful or unwanted use of a domain name or the underlying website content. It is an empirical and conceptual contribution to the online content regulation debate, with specific focus on ...
Sebastian Felix Schwemer
doaj   +1 more source

Learning to Discover Domain-Specific Web Content [PDF]

open access: yesProceedings of the Eleventh ACM International Conference on Web Search and Data Mining, 2018
The ability to discover all content relevant to an information domain has many applications, from helping in the understanding of humanitarian crises to countering human and arms trafficking. In such applications, time is of essence: it is crucial to both maximize coverage and identify new content as soon as it becomes available, so that appropriate ...
Kien Pham, Aécio Santos, Juliana Freire
openaire   +1 more source

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