Results 61 to 70 of about 1,230,989 (267)

Research on Natural Language Misleading Content Detection Method Based on Attention Mechanism

open access: yesIEEE Access
The rapid evolution of digital communication and the corresponding surge in deceptive or misleading content have underscored the critical need for reliable and domain-adaptive detection technologies. Within the scope of the Frontiers in Computer Science,
Boning Liu
doaj   +1 more source

Factors Affecting the Folding of Pseudomonas aeruginosa OprF Porin into the One-Domain Open Conformer

open access: yesmBio, 2010
Pseudomonas aeruginosa OprF is a largely monomeric outer membrane protein that allows the slow, nonspecific transmembrane diffusion of solutes. This protein folds into two different conformers, with the majority conformer folding into a two-domain ...
Etsuko Sugawara   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The Dysferlin Domain-Only Protein, Spo73, Is Required for Prospore Membrane Extension in Saccharomyces cerevisiae

open access: yesmSphere, 2016
Sporulation of Saccharomyces cerevisiae is a developmental process in which an ascus containing four haploid spores forms from a diploid cell. During this process, newly formed membrane structures called prospore membranes extend along the nuclear ...
Yuuya Okumura   +9 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Unsupervised content and style learning for multimodal cross-domain image translation

open access: yesScientific Reports
Recently, impressive progress has been made in cross-domain image translation using image generation models pre-trained on massive amounts of data since these pre-trained generative models have strong generative capabilities.However, due to the fact that
Zhijie Lin   +5 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

A Fungus-Specific Protein Domain Is Essential for RasA-Mediated Morphogenetic Signaling in Aspergillus fumigatus

open access: yesmSphere, 2016
Ras proteins function as conserved regulators of eukaryotic growth and differentiation and are essential signaling proteins orchestrating virulence in pathogenic fungi.
Qusai Al Abdallah   +4 more
doaj   +1 more source

Secure Domain Architecture for Interoperable Content Distribution [PDF]

open access: yes, 2009
Authorized domains are used to share digital content among multiple devices without violating the copyright issues. However, if a domain is composed of multiple devices supporting different DRM technology, sharing and accessing of contents among the multiple devices in a domain may not be possible.
Lei Lei Win   +3 more
openaire   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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