Results 101 to 110 of about 3,046,463 (324)

Unconventional mRNA processing and degradation pathways for the polycistronic yrzI (spyTA) mRNA in Bacillus subtilis

open access: yesFEBS Letters, EarlyView.
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet   +4 more
wiley   +1 more source

Four-dimensional lattice chiral gauge theories with anomalous fermion content

open access: yes, 2007
In continuum field theory, it has been discussed that chiral gauge theories with Weyl fermions in anomalous gauge representations (anomalous gauge theories) can consistently be quantized, provided that some of gauge bosons are permitted to acquire mass ...
D. Kadoh   +9 more
core   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Kolmogorov Complexity and Information Content [PDF]

open access: yesarXiv, 2017
In this paper, we revisit a central concept in Kolmogorov complexity in which one would equate program-size complexity with information content. Despite the fact that Kolmogorov complexity has been widely accepted as an objective measure of the information content of a string, it has been the subject of many criticisms including the fundamental one ...
arxiv  

Approximation of length minimization problems among compact connected sets [PDF]

open access: yes, 2014
In this paper we provide an approximation \`a la Ambrosio-Tortorelli of some classical minimization problems involving the length of an unknown one-dimensional set, with an additional connectedness constraint, in dimension two. We introduce a term of new
Bonnivard, Matthieu   +2 more
core   +2 more sources

On the complexity and the information content of cosmic structures

open access: yes, 2016
The emergence of cosmic structure is commonly considered one of the most complex phenomena in Nature. However, this complexity has never been defined nor measured in a quantitative and objective way.
Vazza, Franco
core   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

A Social Work Education Outcome Measure: The Evaluation Self-Efficacy Scale–II

open access: yesSAGE Open, 2017
The Evaluation Self-Efficacy (ESE) scale was designed as an outcome measure for evaluation research courses in social work. A revised version of the Social Cognitive Theory–based ESE (ESE-II) was developed and evaluated in the current study including ...
Gary Holden   +3 more
doaj   +1 more source

On the computational content of the Loeb measure [PDF]

open access: yesarXiv, 2016
The Loeb measure is one of the cornerstones of Nonstandard Analysis. The traditional development of the Loeb measure makes use of saturation and external sets. Inspired by [13], we give meaning to special cases of the Loeb measure in the weak fragment $\textsf{P}$ of Nelson's internal set theory from [1].
arxiv  

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

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