Results 51 to 60 of about 7,650,707 (279)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Popularity Prediction [PDF]

open access: yes, 2017
With the rise in popularity of the Internet, data describing unique types of items has been collected into easy to access sources. Using this newly acquired data, is it possible to predict if an item will become a bestseller while another fade away with ...
Furgiuele, Andrew
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Social Media Popularity Prediction Based on Multi-Modal Self-Attention Mechanisms

open access: yesIEEE Access, 2022
Popularity prediction using social media is an important task because of its wide range of real-world applications such as advertisements, recommendation systems, and trend analysis.
Hung-Hsiang Lin   +4 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Content popularity prediction in Fog-RANs:a Bayesian learning approach

open access: yes, 2022
In this paper, the content popularity prediction problem in cache-enabled fog radio access networks (F-RANs) is investigated. In order to predict the content popularity with high accuracy and low complexity, we propose a Gaussian process based Poisson ...
Tao, Y. (Yunwei)   +4 more
core  

Dynamic content popularity prediction based on spatial-temporal feature in vehicular networks

open access: yesIntelligent and Converged Networks
Content popularity is crucial for edge caching in vehicular networks, where prediction accuracy directly impacts communication performance. To enhance prediction accuracy by fully exploiting the characteristics of content popularity, we propose a novel ...
Ying Shi   +4 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Understanding Multimodal Popularity Prediction of Social Media Videos With Self-Attention

open access: yesIEEE Access, 2018
Predicting popularity of social media videos before they are published is a challenging task, mainly due to the complexity of content distribution network as well as the number of factors that play a part in this process.
Adam Bielski, Tomasz Trzcinski
doaj   +1 more source

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li   +11 more
wiley   +1 more source

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