Results 81 to 90 of about 737,946 (260)

Structuring the Infosphere Online: Web Search Engines as Protagonists of Content Moderation

open access: yesGlobal Media Journal: German Edition
The World Wide Web (WWW) is an open data space on the Internet. The number of websites accessible on the WWW is so vast that web search engines are essential as structuring and orientation tools for its use.
Jonathan D. Geiger
doaj   +1 more source

Early‐Phase Research in Pediatric Neuro‐Oncology

open access: yes
Pediatric Blood &Cancer, EarlyView.
Jonathan Cunningham
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

A method of semantic search for educational content based on multi-agent technologies

open access: yesСучасний стан наукових досліджень та технологій в промисловості
The digital transformation of industry is accompanied by the active adoption of new technologies and the rapid evolution of production processes. A significant portion of educational materials is distributed across various information sources, including
Олексій Шапиро   +1 more
doaj   +3 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Content-Based Search Tools for Large Sets of Print and Manuscript Music

open access: yesTransactions of the International Society for Music Information Retrieval
We describe the experiences made at the Bavarian State Library with implementing content-based music search for a subset of collections held at a major research library.
Jürgen Diet, Janosch Umbreit
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Mobile Apps for Heart Rate Variability: App Store Search and Content Analysis

open access: yesJMIR Cardio
BackgroundHeart rate variability (HRV) is a noninvasive indicator of autonomic nervous system activity that is increasingly used for health and performance monitoring.
Eline de Jager   +3 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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