Results 91 to 100 of about 6,751,266 (313)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Content Validity of Instruments in IS Research [PDF]

, 2006
This paper presents a literature review of content validity, summarizes qualitative and quantitative approaches for content validity assessment, and explores the extent to which IS researchers have content validated their developed instruments.
Tojib, Dewi Rooslani, Sugianto, Ly-Fie
core  

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Content validity by ten experts (n = 10).

, 2019
Content validity by ten experts (n = 10).
Mikyeong Cho (7878803), Youlim Kim (5575388), Hyeonkyeong Lee (6829505), Young-Me Lee (7878806), Sookyung Kim (4789179), Ja-yin Lee (7878809), Haeyoung Min (7878812)   +6 more
core   +1 more source

Content validity utilizing patient evaluation of Item importance and clarity.

, 2021
Content validity utilizing patient evaluation of Item importance and clarity.
Wendy Madden (11570552), Bruce J. Trock (11054043), Ayodeji Sotimehin (11570558), Arthur L. Burnett (7926023), Yuezhou Jing (11570561), Belinda F. Morrison (11570549), Monika Asnani (11570555), Uzoma Anele (252581)   +7 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Navigating interconnected complexities: validation and reliability of an instrument for sustainable development of education 5.0

Cogent Education
Sustainability actions in Higher Education Institutions (HEIs) profoundly affect students, employees and their communities. These aim at social and economic benefits for local communities.
María Soledad Ramírez-Montoya, Claudia Marina Vicario-Solorzano, Laura Icela González-Pérez   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Pengembangan Media Film Dokumenter Yang Diangkat Dari Hasil Penelitian Pertumbuhan Anak Di Desa Jungkat

Jurnal Kajian Teknologi Pendidikan
The learning media that lacks support can hinder communication between teachers and students. Engaging and innovative learning media can enliven the atmosphere during the learning process.
Khofifah Azmi Bilqis, Wolly Candramila, Asriah Nurdini Mardiyyaningsih   +2 more
doaj   +1 more source