Results 101 to 110 of about 6,751,266 (313)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Content validity of STEMTIP using CVR method

open access: yes, 2018
This study aims to examine the content validity of STEM Teachers’ Instructional Preparedness (STEMTIP) for Malaysian science teachers using Content Validity Ratio (CVR). Fifteen experts selected via purposive sampling evaluated the content.
Abdul Manaf, Umi Kalthom   +3 more
core   +1 more source

Development of mathematical thinking test: content validity process / Nurul Akmal Md Nasir ... [et al.] [PDF]

open access: yes, 2022
Validity is the extent to which an instrument measures what it is to measure. The instrument's validity is assessed by confirming the instrument's capability to measure the intended measurement.
Rasid, Nor Syazwani   +4 more
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Content validity: The source of my discontent.

open access: yes, 1977
The concept of content validity takes on special importance where invoked to justify use of a test. The term 1) refers to psychological measurement, 2) using samples of behavior, sampling both stimulus and response components, and 3) implies ...
Guion, Robert M
core   +1 more source

Measuring the Quality of Student Support Services in Open Distance E-Learning

open access: yes, 2020
Student support services are essential elements in the success of open distance e-learning. These services help students to become competent in achieving their goals.
Aberra, Tsige, GebreMeskel
core   +1 more source

Development and Content Validation of a Novel Iliotibial Band Friction Syndrome Index Questionnaire: A Cross-sectional Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Introduction: The Iliotibial Band Friction Syndrome (ITBFS) diagnosis is based on clinical reasoning. Ober’s test and the Noble compression test are examples of diagnostic techniques, but there is no specific diagnostic standard assessment questionnaire ...
Ritika Kashyap   +5 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

A Review and Content Validation of 10 Measurement Scales for Parental Mediation of Children’s Internet Use

open access: yesInternational Journal of Communication, 2021
For the last decade, research has shown inconsistent findings about validity of parental mediation scales for children’s Internet use. This inconsistency has manifested itself in at least 10 parental mediation models, which are also inconsistent in ...
Seffetullah Kuldas   +3 more
doaj  

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