Results 61 to 70 of about 6,751,266 (313)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Adolescent Assertiveness Assessment Scale: Evidence of Content Validity
Psicologia: Teoria e PesquisaThis study aimed to present the process of elaborating the Adolescent Assertiveness Assessment Scale (AAA-S). Based on the analysis of judges, evidence of the validity of the content of the instrument was established, assessing the criteria of relevance,
Sara Luize Pereira de Lima +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Content validity index of questions items.
, 2019 Content validity index of questions items.
Olanrewaju O. Oyedepo (6294005) +9 more
core +1 more source
Open Journal of Occupational Therapy, 2017 Background: With the increasing complexity of care, people with disabilities and supportive significant others (SSO) must often coordinate key aspects of their own care, but no validated scale currently exists to comprehensively characterize the ...
Brian P. Johnson, Mark V. Johnston
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Item and Scale Content Validity Indexes.
, 2016 Item and Scale Content Validity Indexes.
Leanne Chalmers (564165) +2 more
core +1 more source
Content validity index by 5 experts.
, 2023 This study aimed to validate a translated and culturally adapted version of the Infant Feeding Intentions (IFI) Scale for use in Thailand. Prenatal breastfeeding intention is a strong indicator of breastfeeding initiation.
Ratchanok Phonyiam (12896674) +2 more
core +1 more source