Results 61 to 70 of about 486,384 (263)

Navigating interconnected complexities: validation and reliability of an instrument for sustainable development of education 5.0

Cogent Education
Sustainability actions in Higher Education Institutions (HEIs) profoundly affect students, employees and their communities. These aim at social and economic benefits for local communities.
María Soledad Ramírez-Montoya, Claudia Marina Vicario-Solorzano, Laura Icela González-Pérez   +2 more
doaj   +1 more source

Designing a family promotion and formation training package [PDF]

Faṣlnāmah-i Farhang Mushavirah va Ravān/Darmānī
Over recent decades, Iran’s marriage patterns have undergone substantial transformation, accompanied by a lack of systematic, evidence-based interventions and conceptual coherence in educational programs concerning family formation.
elahe Hosni Hanzaei, Mohammad Hasan Lotfi, masume dashtabadi, Hasan Zare KHormizi   +3 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Pengembangan Media Film Dokumenter Yang Diangkat Dari Hasil Penelitian Pertumbuhan Anak Di Desa Jungkat

Jurnal Kajian Teknologi Pendidikan
The learning media that lacks support can hinder communication between teachers and students. Engaging and innovative learning media can enliven the atmosphere during the learning process.
Khofifah Azmi Bilqis, Wolly Candramila, Asriah Nurdini Mardiyyaningsih   +2 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Development and Content Validation of a Novel Iliotibial Band Friction Syndrome Index Questionnaire: A Cross-sectional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: The Iliotibial Band Friction Syndrome (ITBFS) diagnosis is based on clinical reasoning. Ober’s test and the Noble compression test are examples of diagnostic techniques, but there is no specific diagnostic standard assessment questionnaire ...
Ritika Kashyap, Manu Goyal, Aditi Nagpal, Chhaya, Muskan Bathla, Kanu Goyal   +5 more
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source