FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Effects of Household Processing on Rutin and Fagopyrin F in Common and Tartary Buckwheat. [PDF]
FoodsKim J, Lee SA, Kim J.
europepmc +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Dissolution Behavior of Mineral Elements in Dahongpao Tea, Its Association with Flavor Quality, and Potential Contribution of Infusions to Dietary Reference Intakes. [PDF]
FoodsJia M +7 more
europepmc +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Effect of PPC Content on the Structure and Properties of PBAT/PLA/PPC Ternary Composite Mulch Films. [PDF]
Polymers (Basel)Xu R, Zheng Z, Lou Z, Xu L.
europepmc +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Foliar Selenium Application Enhances Wheat Resistance to <i>Bipolaris sorokiniana</i>-Induced Spot Blotch via Modulation of Growth, Physiological Homeostasis, and Antioxidant Defense Systems. [PDF]
Life (Basel)Raheel M +10 more
europepmc +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Regulatory effects of salt-nitrogen interaction on the growth and photosynthetic characteristics of <i>Limonium bicolor</i> in the Yellow River Delta. [PDF]
Front Plant SciNie L +9 more
europepmc +1 more source