Results 121 to 130 of about 6,384,811 (263)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Contents IJG

Indonesian Journal of Geography, 2017
Contents IJG
doaj   +1 more source

Dietary Bazhen San solid-state fermentation product improves laying performance, immunity and intestinal health in laying hens during the late laying period. [PDF]

Front Immunol
Zhao Z, Wang X, Bao Y, Meng J, Gong J, Zhang L, Li Z, Yao W, Chuo Y, Shi W, Li J.   +10 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

<i>Alcea rosea</i> L. responses to Cd and Pb stress: phenotypic, physiological, subcellular, chemical speciation, and ultrastructural analyses. [PDF]

Front Plant Sci
Liao J, Luo Y, Yang H, Deng W, Bai J, Pan Y, Jiang B, Jia Y.   +7 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Seed quality and nutritional composition of conventional and zinc biofortified wheat under hermetic and conventional storage techniques. [PDF]

Sci Rep
Muazzam M, Bakhtavar MA, Farooq U, Iqbal S, Ahmad S, Iqbal M, Saeed SQ, Sadaf T.   +7 more
europepmc   +1 more source

Contents [PDF]

, 2003

core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Reappraising intuitions about consciousness. [PDF]

Front Psychol
Kim C, Chong SC.
europepmc   +1 more source