Results 201 to 210 of about 2,448,608 (243)

Development and Characterization of Low-Glycemic Couscous Enriched With β-Glucans and Proteins. [PDF]

Food Sci Nutr
Surek E, Ozkan K, Ozer C, Jilal A, Salih G, Yildirim H, Visioni A, Sestili F, Aktas-Akyildiz E, Sagdic O, Koksel H.   +10 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Effects of Glass Fiber Content on the Cellular Morphology and Mechanical Properties of Microcellular Injection-Molded Polypropylene Composite Foams. [PDF]

Polymers (Basel)
Zhang H, Guo W.
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Is direct oxidative damage of bone collagen associated with poor human cortical bone tissue fracture resistance? [PDF]

JBMR Plus
Dapaah DY, Arakawa S, Carroll GA, Wang Y, McLachlin S, Saito M, Willett TL.   +6 more
europepmc   +1 more source

Contents [PDF]

, 2015
Contents
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Effects of Foliar Calcium and Magnesium Application on Peach (<i>Prunus persica</i> L.) Nutrition Status and Fruit Quality Formation. [PDF]

Plants (Basel)
Lu C, Wang X, Guo X, Hussain B, Wang S, Yang X.   +5 more
europepmc   +1 more source

The sulfur content and isotopic composition of the subarc mantle. [PDF]

Sci Adv
Taracsák Z, Mather TA, Plank T, Peccia A, Ding S, Monteleone B, Aiuppa A, Pyle DM.   +7 more
europepmc   +1 more source