Results 91 to 100 of about 18,638,364 (298)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

PV-Optimized Heat Pump Control in Multi-Family Buildings Using a Reinforcement Learning Approach

Energies
For the energy transition in the residential sector, heat pumps are a core technology for decarbonizing thermal energy production for space heating and domestic hot water.
Michael Bachseitz, Muhammad Sheryar, David Schmitt, Thorsten Summ, Christoph Trinkl, Wilfried Zörner   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Term Context [PDF]

Formalized Mathematics, 2014
Summary Two construction functors: simple term with a variable and compound term with an operation and argument terms and schemes of term induction are introduced. The degree of construction as a number of used operation symbols is defined. Next, the term context is investigated.
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Transformation to learning from a distance

MedEdPublish, 2020
COVID-19 is a strong disruptive force that has not only influenced our global health and economy but also has changed the way we teach, learn and communicate with our students.
David Taylor, Janet Grant, Hossam Hamdy, Leonard Grant, Hesham Marei, Manda Venkatramana   +5 more
doaj  

Editorial: Context in Context [PDF]

Foundations of Science, 2002
Edmonds, B., Akman, V.
openaire   +2 more sources

Context-Aware Generative Adversarial Privacy

, 2017
Preserving the utility of published datasets while simultaneously providing provable privacy guarantees is a well-known challenge. On the one hand, context-free privacy solutions, such as differential privacy, provide strong privacy guarantees, but often
Chen, Xiao, Huang, Chong, Kairouz, Peter, Rajagopal, Ram, Sankar, Lalitha   +4 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Fostering teacher–student relationship-building competence: a three-year learning trajectory for initial pre-primary and primary teacher education

Frontiers in Education
It is widely acknowledged that high-quality teacher-student relationships contribute to both student and teacher well-being. However, research shows that building these relationships can be challenging for teachers and signals opportunities for teacher ...
Liedewij F. N. Borremans, Helma M. Y. Koomen, Jantine L. Spilt, Jantine L. Spilt   +3 more
doaj   +1 more source