Results 101 to 110 of about 22,713,326 (323)

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

PV-Optimized Heat Pump Control in Multi-Family Buildings Using a Reinforcement Learning Approach

open access: yesEnergies
For the energy transition in the residential sector, heat pumps are a core technology for decarbonizing thermal energy production for space heating and domestic hot water.
Michael Bachseitz   +5 more
doaj   +1 more source

Terminal context in context-sensitive grammars [PDF]

open access: yes
Context-free language generation using nontrivial constraints on context-sensitive grammar ...
Book, R. V.
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Context-Awareness

open access: yes, 2008
Context-aware computing has increasingly gained the attention of the research community because, as it is the case with human interactions, context information provides the background against which it is possible to more accurately interpret communicative acts without the need to explicitly state everything that might be relevant.
Bruno Gonçalves   +2 more
openaire   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

A Braille Trail for all: Inclusive design in the Karoo Desert National Botanical Garden

open access: yesAfrican Journal of Disability
Background: Disability-inclusive public green spaces are vital for universal accessibility and for enhancing accessible tourism. Integrating multisensory stimuli with information and communication technologies fosters inclusive, sustainable, interactive,
Susanna F. Greyling   +2 more
doaj   +1 more source

Law Clerks Out of Context [PDF]

open access: yes, 2010
[Excerpt] “In a previous article, I examined judicial opinions in cases in which law clerks have gone wild, principally by doing things that law clerks just aren‘t supposed to do, such as convening court, conducting independent factual investigations ...
Potter, Parker B., Jr.
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Fostering teacher–student relationship-building competence: a three-year learning trajectory for initial pre-primary and primary teacher education

open access: yesFrontiers in Education
It is widely acknowledged that high-quality teacher-student relationships contribute to both student and teacher well-being. However, research shows that building these relationships can be challenging for teachers and signals opportunities for teacher ...
Liedewij F. N. Borremans   +3 more
doaj   +1 more source

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