Results 141 to 150 of about 7,046,818 (296)

Strategies for Translating Obscenity: Medical Language and Sanitization in Malay Rāychoudhurī’s Poetry

open access: yesSanglap: Journal of Literary and Cultural Inquiry, 2018
The Bengali ‘obscene’ (aślīl) poetry of the Hungry Generation is heavily pregnant with ‘dirty’ sexual imagery. In particular, the poem “Prachanda Baidyutik Chutar” and its English translation “Stark Electric Jesus” (1964) by the Hungryalist Malay ...
Daniela Cappello
doaj  

Analyzing the Modeling of Context with Ontologies

open access: yes, 2007
Ontologies are a widely accepted instrument for the modeling of context information. We consider the identification of the benefits and difficulties of ontology-based modeling to be an important next step to further improve the usability of ontologies in
Strang, Thomas   +3 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

[Portrait of Dr Judith Winternitz, team leader, Cultural Context of Unemployment Project, Canberra, 8 November, 1985] [picture].

open access: yes, 1985
Title devised by cataloguer.; Part of collection: Putting faces to names.; "A long waited cup of coffee, "one more please!", Canberra 8/11/85"--Label on reverse.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic ...

core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

“Providing context aware learning services to learners with portable devices”

open access: yes, 2010
[[abstract]]Context aware learning service is an interactive model between learners and learning services based on learners' surrounding learning environments.
Yang, S.J.H.; Chen, I.Y.L.
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

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