Results 31 to 40 of about 601,139 (216)

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba   +29 more
wiley   +1 more source

RESILIENCE IN THE CONTEXT OF THE SOCIO-POLITICAL SITUATION OF YOUNG ADULTS IN EUROPE

open access: yesHumanities and Social Sciences, 2023
As the epidemiological statistics for anxiety disorders and mood disorders show, adult mental health has declined in recent decades, making the life of the average person more prone to adversity.
Agnieszka FRANCZOK-KUCZMOWSKA   +1 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Impact of Public Transport Context Situation and Culture on Mode Choice

open access: yesSocial Sciences, 2019
Arrival on time when reaching a trip destination is perceived differently by different communities, but the need to arrive at the desired time is essential.
Miguel Loyola   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

THE CONTEXT OF SITUATION AND CONTEXT OF CULTURE (GENRE) IN THE VIDEO TUTORIALS ON YOUTUBE CHANNEL: A FUNCTIONAL DISCOURSE APPROACH

open access: yesSocial Sciences, Humanities and Education Journal, 2022
This study examines the contexts of the videos in YouTube videos of Devina Hermawan. In examining the contexts of the videos, the researcher adopts Halliday’s systemic functional linguistics (SFL).
Atina Firdausa Qisthi   +2 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Les rôles du co-texte, du contexte et de la situation dans la lecture en langue étrangère et leur implication pour la lexicographie bilingue

open access: yesCorela, 2012
This study aims to identify co-text, context, and situation roles in the construction of meaning in reading by putting into practice a pedagogical approach during French for Specific Purposes classes.
Sandra Dias Loguercio
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

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