Results 71 to 80 of about 4,049,351 (298)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Improving situation awareness of a single human operator interacting with multiple unmanned vehicles: first results [PDF]
, 2010 In the context of the supervision of one or several unmanned vehicles by a human operator, the design of an adapted user interface is a major challenge.
Aubert, Thomas +5 more
core
Responding to Sexual Discrimination: The effects of societal versus self-blame [PDF]
, 1994 While self-blame has been considered to be a useful coping tool for victims, its benefits within the context of group discrimination are equivocal. The present research hypothesized that women encouraged to engage in self-blame for sex discrimination ...
Foster, Mindi D +2 more
core +3 more sources
Situational context of environmental university education
E3S Web of ConferencesThe scientific interest in improving the environmental training of university students emphasizes the training technology associated with the disclosure of their personal and professional potential through inclusion in the joint solution of environmental problems not in abstract but in real life situations.
Kamerilova Galina +4 more
openaire +2 more sources
Cognitive simulation of educational migration trends and conditions in the context of universities' competitiveness [PDF]
, 2017 The article conteins the cognitive model for studying the educational migration trends and factors. Scenarios of situation development were implemented: optimistic, realistic and pessimistic that allows to forming methodical recommendations for improving
Bilan, Yuliia Andriivna +2 more
core
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Evidence of audience in MS Hunter 93, a medical text
Revista de Lenguas para Fines Específicos, 2015 The aim of this paper is to explore the concept and evidence of audience in the text of MS Hunter 93 (T.4.10), a remedy book written in the second half of the 16th century (c.a. 1565).
Ivalla Ortega Barrera
doaj
THE DEMOGRAPHIC SITUATION AND THE REGIONAL DEVELOPMENTS IN THE CONTEXT OF REGIONAL POLICY [PDF]
Journal of Bio-Based Marketing, 2021 The development of scientific knowledge in recent years has necessitated the systematization of regional issues through the prism of the population and settlements.
Michaela Georgieva
doaj