Results 61 to 70 of about 4,049,351 (298)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Sexual Violence and Relationship Abuse among College Students: The Bystander Intervention Process [PDF]

open access: yes, 2014
This project investigated how college students describe bystander intervention in the context of sexual violence and relationship abuse compared to intervention in a general helping situation.
Wible, Elizabeth J
core   +1 more source

Introducing systems engineering to industrial design engineering students with hands-on experience [PDF]

open access: yes, 2005
The article presents an innovative educational project to introduce systems engineering to third year students in industrial design engineering at the University of Twente. In a short period the students are confronted with new technology, namely sensors
Bonnema, G. Maarten   +2 more
core   +2 more sources

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

RHETORIC IN THE CONTEXT OF THE POST-TRUTH SITUATION

open access: yesЕпістемологічні дослідження у філософії, соціальних і політичних науках
This article analyzes the origins and significance of rhetoric as an effective means of control through modal power exercised by free citizens of the classical Athenian polis.
Вадим ПАЛАГУТА
doaj   +1 more source

XML data integrity based on concatenated hash function [PDF]

open access: yes, 2009
Data integrity is the fundamental for data authentication. A major problem for XML data authentication is that signed XML data can be copied to another document but still keep signature valid. This is caused by XML data integrity protecting.
Liu, B, Lu, J, Yip, YJ
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Structure of a Psychotherapeutic Situation in the Context of the Orthodox-oriented Approach

open access: yesКонсультативная психология и психотерапия, 2015
The article introduces a model of a psychotherapeutic situation structure in the context of the Orthodox-oriented approach, which helps a psychologist to consider spiritual reality in psychotherapeutic case analysis.
Drozdov D.S.
doaj   +1 more source

Automatic Detection of Myocontrol Failures Based upon Situational Context Information [PDF]

open access: yes2019 IEEE 16th International Conference on Rehabilitation Robotics (ICORR), 2019
Myoelectric control systems for assistive devices are still unreliable. The user's input signals can become unstable over time due to e.g. fatigue, electrode displacement, or sweat. Hence, such controllers need to be constantly updated and heavily rely on user feedback.
Heiwolt, Karoline   +4 more
openaire   +4 more sources

A personalized and context-aware news offer for mobile devices [PDF]

open access: yes, 2016
For classical domains, such as movies, recommender systems have proven their usefulness. But recommending news is more challenging due to the short life span of news content and the demand for up-to-date recommendations.
A Følstad   +18 more
core   +1 more source

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