Results 121 to 130 of about 1,493,771 (318)

Fathers, Families, and Society: A Two-Decade Systematic Literature Review on the Contexts and Consequences of Paternity and Parental Leave for Fathers

Social Sciences
This systematic literature review assesses two decades of the literature on paternity and parental leave for fathers. We developed a conceptual framework that broadens the understanding of why fathers (do not) use paternity and/or parental leave, and the
Stéfanie André, Nola Cammu, Eline Meuleman   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

HERMENEUTICAL PRINCIPLES OF QUALITY MANAGEMENT OF THE LABOR FORCEH [PDF]

Sovremennye Issledovaniâ Socialʹnyh Problem, 2012
The problem of quality of the workforce for the innovation economy is an extremely relevant and depends on the accepted ideology of quality management training.
Valentina Kiseleva
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

De jeugd van tegenwoordig. Emancipatie van liefde en lust sinds 1880. [PDF]

, 2012
Sinds 1880 is de jeugd van tegenwoordig grondig veranderd, samen met de verhoudingen tussen de generaties, de seksen en de sociale klassen. Dat bracht ophef en soms morele paniek teweeg, zoals over seksualisering: van krimpende roklengtes en ...
Leerstoel Vollebergh, Wouters, Cas, Youth in Changing Cultural Contexts   +2 more
core  

Guest editorial: Higher education research of master students: nurturing their development, hearing their voices, and promoting their expectations [PDF]

Higher Education Evaluation and Development
Hugo Horta, Jisun Jung
doaj   +1 more source

THE CHANGING FACE OF ORATURE IN POSTCOLONIAL NIGERIA

Proverbium, 2013
The coming into being of creative writing in English in post-colonial Nigeria since independence and the eminence attained in it as an expressive form by Achebe, Soyinka, Clark, Okigbo and many others, is a cultural revolution.
Nereus Yerima Tadi
doaj  

Social prediction errors in assisting strangers: the role of outcomes and contexts

Frontiers in Psychology
IntroductionHelping behavior is a fundamental aspect of social interaction, yet little is known about how accurately helpers can predict the emotional responses of help-seekers, particularly when interacting with strangers.MethodsThis study investigated ...
Yan Li, Zhiwei Liu
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source