Results 111 to 120 of about 2,003,896 (299)

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

THE CHANGING FACE OF ORATURE IN POSTCOLONIAL NIGERIA

open access: yesProverbium, 2013
The coming into being of creative writing in English in post-colonial Nigeria since independence and the eminence attained in it as an expressive form by Achebe, Soyinka, Clark, Okigbo and many others, is a cultural revolution.
Nereus Yerima Tadi
doaj  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Social prediction errors in assisting strangers: the role of outcomes and contexts

open access: yesFrontiers in Psychology
IntroductionHelping behavior is a fundamental aspect of social interaction, yet little is known about how accurately helpers can predict the emotional responses of help-seekers, particularly when interacting with strangers.MethodsThis study investigated ...
Yan Li, Zhiwei Liu
doaj   +1 more source

The context of contextualizing contexts [PDF]

open access: yes, 2016
Welter, Friederike   +2 more
openaire   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Language teaching in blended contexts

open access: yes, 2012
Book review of: Language teaching in blended contexts, edited by M. Nicolson, L. Murphy, and M. Southgate, Edinburgh, Dunedin Academic Press, 2011, xx + 279 pp., £18.95 (paperback), ISBN 978-1-906716-20-
Poole, Trisha
core   +1 more source

The Role of Contexts in Educational and Employment Transitions and Pathways of Young People

open access: yesSocial Inclusion
Young people’s educational and employment pathways are shaped by the social contexts in which they are embedded. While past research has often emphasized individual characteristics, this thematic issue highlights the decisive role of contextual factors ...
Alexandra Wicht   +3 more
doaj   +1 more source

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