Results 111 to 120 of about 3,685,645 (304)
Formal Contexts, Formal Concept Analysis, and Galois Connections
, 2013 Formal concept analysis (FCA) is built on a special type of Galois connections called polarities. We present new results in formal concept analysis and in Galois connections by presenting new Galois connection results and then applying these to formal ...
Denniston, Jeffrey T. +2 more
core +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Teaching Edith Eaton/Sui Sin Far: Multiple Approaches [PDF]
, 2010 This essay compares pedagogical approaches to teaching the literature of Edith Eaton in two distinct contexts: a course on Asian American Literature and a course on Asian Americans of Mixed Heritage.
Dariotis, Wei Ming
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Guest editorial: Higher education research of master students: nurturing their development, hearing their voices, and promoting their expectations [PDF]
Higher Education Evaluation and DevelopmentHugo Horta, Jisun Jung
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Rotationally invariant 3D shape contexts using asymmetry patterns [PDF]
, 2013 This paper presents an approach to resolve the azimuth ambiguity of 3D Shape Contexts (3DSC) based on asymmetry patterns. We show that it is possible to provide rotational invariance to 3DSC at the expense of a marginal increase in computational load ...
Sukno, Federico M. +2 more
core +2 more sources
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
International Journal of Child Care and Education PolicyUsing a mixed research design, the overall objective of this study is to investigate the profiles of child labour in Ethiopia’s districts of Raya-Kobo and Angot.
Mengistu Abate Weldeyesus +1 more
doaj +1 more source