Results 91 to 100 of about 2,003,896 (299)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Ecological Constraints of Timescales, Production, and Perception in Temporal Experiences of Music

open access: yesEmpirical Musicology Review, 2015
In trying to structure our discussions of temporal experience in music, it could be useful to look at some basic ecological constraints of timescales, production, and perception of music.
Rolf Inge Godøy
doaj   +1 more source

How Context Influences Our Perception of Emotional Faces: A Behavioral Study on the Kuleshov Effect

open access: yesFrontiers in Psychology, 2017
Facial expressions are of major importance in understanding the mental and emotional states of others. So far, most studies on the perception and comprehension of emotions have used isolated facial expressions as stimuli; for example, photographs of ...
Marta Calbi   +6 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Les transformations actuelles de l’EEE

open access: yesMesure et Évaluation en Éducation, 2012
Dans cet article conclusif, les transformations actuelles de l’EEE sont interrogées selon trois axes. Les limites et les dérives observées dans ce domaine conduisent tout d’abord à remettre en question une approche de la qualité de l’enseignement ...
Nathalie Younès, Marc Romainville
doaj   +1 more source

Career counseling research-practice disparities: What we know and what we need to know

open access: yesSouth African Journal of Education, 2017
The most practical principle in contextualisation emanates from our understanding of the experience of everyday life. However, this principle is not confined to such understanding.
Maria Eduarda Duarte
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Selecting Contexts. One Method of Selecting Contexts for Theatre Historiography

open access: yes, 2016
In principle, the world and life itself are the contexts of theatrical events. The term context is broad and thus seems hardly usable. It only makes sense to use the term when terminologies and methodologies determine which parts of their contexts are to
Kotte, Andreas
core  

Electronic literature: contexts and poetics [PDF]

open access: yes, 2018
Electronic literature, essentially, must be electronic and literary. Even if we cannot define the literary, we can at least recognize it, and, from recognition, we can begin to build meaning.
Davin Heckman   +4 more
core   +1 more source

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