Results 81 to 90 of about 1,493,771 (318)
Variations on a middle class theme: English primary schools in socially advantaged contexts [PDF]
Multiple contexts interact to position any school on a spectrum from cumulatively advantaged to cumulatively disadvantaged. This article discusses a study of the contextual advantages and disadvantages experienced by primary schools in the south east of ...
Lupton, Ruth +3 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
In this presentation we give a short reminder on the origin of the two main notions of context that are used in philosophy of language in order to draw attention to the main points of discussion common in the meeting on “Contexts in Philosophy”
VIGNOLO, MASSIMILIANO, PENCO, CARLO
core
Building on Wittgenstein’s theory of ordinary language use and Lamin Sanneh’s insights into the effects of biblical translations in vernacular languages, this essay examines how the translation process in Niu Tireni (New Zealand/Aotearoa) in the 1830s ...
Samuel D. Carpenter
doaj +1 more source
A presente pesquisa teve como objetivo investigar a correlação entre as crenças e práticas de cuidado materno em diferentes contextos no município de Itajaí. Participaram da pesquisa setenta e sete mães que responderam a um questionário.
Ana Paula Ribeiro Kobarg +1 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Compassion and empathy in educational contexts [PDF]
Compassion and empathy are key attributes to living a healthy and happy life. Surprisingly, there is little written about how these qualities can be taught to children and young people, as well as how teachers can model these traits in their teaching ...
core +1 more source
The growth in the adoption of circular economy principles in the construction industry has given rise to material passports as a critical implementation tool.
Lawrence Martin Mankata +3 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source

