Results 61 to 70 of about 2,003,896 (299)

Wellbeing in Educational Contexts

open access: yes, 2020
Wellbeing has been identified as a serious issue for principals, teachers and students within educational contexts. The problem of principal health and wellbeing has also been recognised at both national and state levels in Australia for the at least a ...
Carter, Susan, Andersen, Cecily
core   +1 more source

Context Tuning for In-Context Optimization

open access: yesCoRR
We introduce Context Tuning, a simple and effective method to significantly enhance few-shot adaptation of large language models (LLMs) without weight updates. In-Context Learning (ICL) forms a memory representation of the demonstrations in a single forward pass but cannot refine it when insufficient.
Jack Lu   +3 more
openaire   +2 more sources

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Introduction : transitional justice in aparadigmatic contexts

open access: yes, 2023
This introduction provides the rationale and theoretical anchoring for the volume and its focus on aparadigmatic cases. It argues that practice and scholarship in paradigmatic transitional justice contexts built a field that conceptualises the state as a
Carlson, Kerstin Bree   +5 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Editorial : towards an enhancement of knowledge generation in marketing by contributions from non-western contexts [PDF]

open access: yes, 2014
This editorial paper highlights the significance of scholarly contributions from non-western contexts to business and management studies in general and marketing in particular.
Jafari, Aliakbar
core   +3 more sources

Adolescents' resilience in the face of cannabis use offers: the role of cannabis-specific contexts and cognitions

open access: yesFrontiers in Adolescent Medicine
ObjectiveAdolescents who refrained from using cannabis despite having opportunities to do so represent an increasingly relevant group amid concerns about growing cannabis availability.
Jasmina Burdzovic Andreas   +1 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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