Results 141 to 150 of about 6,202,666 (342)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Editorial: Sociomateriality in Children With Typical and/or Atypical Development

open access: yesFrontiers in Psychology, 2020
Antonio Iannaccone   +3 more
doaj   +1 more source

Impairment of aversive episodic memories during Covid-19 pandemic: The impact of emotional context on memory processes

open access: green, 2021
Candela S. León   +5 more
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Consumo de bebidas alcohólicas y ambiente social. Un enfoque multinivel Alcohol consumption and social context. A multilevel approach

open access: yesRevista Cubana de Higiene y Epidemiología, 2010
Objetivos: Tradicionalmente las variaciones en el consumo de bebidas alcohólicas se han estudiado en términos de las características individuales. Con este estudio nos propusimos valorar la contribución de los factores contextuales en conjunto con los ...
Martha Chang de la Rosa   +1 more
doaj  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

US State Policy Contexts and Mental Health Among Working-Age Adults. [PDF]

open access: yesMilbank Q
Gutin I   +4 more
europepmc   +1 more source

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