Results 111 to 120 of about 11,389,755 (299)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

The Development of Learning Applications on Linear Equations Using A Contextual Approach

Tarbiyah: Jurnal Ilmiah Kependidikan
This research is motivated by limited learning media development to support students' learning processes. This research uses a contextual approach to test the validity and practicality of learning applications on linear equation material.
Desti Tatian Putri, Susanti Susanti, Puji Astuti   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

A Contextual Approach to the Psychological Study of Identity Concealment: Examining Direct, Interactive, and Indirect Effects of Structural Stigma on Concealment Motivation Across Proximal and Distal Geographic Levels. [PDF]

Psychol Sci, 2021
Lattanner MR, Ford J, Bo N, Tu W, Pachankis JE, Dodge B, Hatzenbuehler ML.   +6 more
europepmc   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Effort To Improve Student Achievement In Learning Through The Development Of Function Composition Method Of Discussion On The Approach To Contextual Teaching And Learning (CTL) In Class XI IPA 1 Salatiga Christian Senior High School 1 [PDF]

, 2011
Learning mathematics in class XI IPA 1 Salatiga Christian Senior High School 1 needs to be improved because teachers are still learning that involves using the lecture method and mechanistic approach.
Dimas Adi Nugroho, Dimas Adi Nugroho, Handita Sari , Handita Sari, Oktavianus Adi Nugraha, Oktavianus Adi Nugraha, Sundo Nurbono, Sundo Nurbono, Kriswandani, Kriswandani   +4 more
core  

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Contextual theology

, 2011
This online resource provides an introduction to the argument that Christian theology is contextual. Presented in clear and short chapters, it includes a glossary and bibliography at the end of the resource.
Pears, Angie
core  

Comparing STEM and contextual approaches' impact on students' motivation and learning in acid-base materials

Edu Sains: Jurnal Pendidikan Sains dan Matematika
This study aimed to compare the impact of science, technology, engineering, and mathematics (STEM) and contextual approaches on students' motivations for learning and achievements in chemistry lessons focused on acid-base materials.
Latief Susila Aji, Muhammad Zamhari, Febri Ilham Saputra, Dewi Masrukhah   +3 more
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source