Results 191 to 200 of about 14,254,520 (384)

Spatial analysis of COVID-19 clusters and contextual factors in New York City

Spatial and Spatio-temporal Epidemiology, 2020
J. Cordes, M. Castro
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Deconstructing and reconstructing diversity in client-provider-relationships of social work

Social Work and Society
Diversity and reflections on diversity impact client-provider-relationships of social work on different levels, ranging from institutionalized programs to interpersonal practices to individual expectations, cognitive make-ups and emotional experiences ...
Lars Alberth, Ellen Kollender, Anke Karber, Philipp Sandermann, Birte Siem   +4 more
doaj  

Theoretical Analysis Model of the Adoption of Reactive and Proactive Eco-Innovation Strategies: the Influence of Contextual Factors Internal and External to Organizations

BBR: Brazilian Business Review, 2014
This article aims to provide research propositions of the relationship between internal and external contextual factors and strategies for reac tive and proactive eco-innovation, defining the theoretical analysis model from these propositi ons. Therefore,
Marlete Beatriz Maçaneiro, Sieglinde Kindl da Cunha   +1 more
doaj  

Implementation of Evidence-Based Practice in Rheumatology: What Sociodemographic, Social Cognitive and Contextual Factors Influence Health Professionals' Use of Research in Practice?

, 2016
M. Neher
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Evaluating the Contextual Integrity of Privacy Regulation: Parents' IoT Toy Privacy Norms Versus COPPA

, 2019
Increased concern about data privacy has prompted new and updated data protection regulations worldwide. However, there has been no rigorous way to test whether the practices mandated by these regulations actually align with the privacy norms of affected
Apthorpe, Noah, Feamster, Nick, Varghese, Sarah   +2 more
core  

Social contextual factors contributing to child and adolescent labor: an ecological analysis [PDF]

, 2011
Vilma Sousa Santana, Martha Itaparica
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source