Contextual factors influencing neuro-affirming practice: Identifying what helps or hinders implementation in health and social care. [PDF]
Gray A +4 more
europepmc +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Beyond Local Champions: Contextual Factors Shaping the Implementation of Healthy Eating Interventions in Centre-Based Care - A Qualitative Study With Educators and Cooks. [PDF]
Chan J +4 more
europepmc +1 more source
A Scoping Review of the Demographic and Contextual Factors in Canada's Educational Opportunity Gaps. [PDF]
Christine Mayor, Eliana Barrios Suarez
openalex
Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Contextual factors associated with neonatal pain responses: clinical observational study. [PDF]
Zhan X +12 more
europepmc +1 more source
Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner +6 more
wiley +1 more source
Neighborhood Environmental and Contextual Factors Improve Prediction of Childhood Body Mass Index: An Application of Novel Graph Neural Networks. [PDF]
Li K +5 more
europepmc +1 more source
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source

