Results 41 to 50 of about 256,465 (275)

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Bayesian estimation of the orthogonal decomposition of a contingency table

open access: yesAustrian Journal of Statistics, 2016
In a multinomial sampling, contingency tables can be parametrized by probabilities of each cell. These probabilities constitute the joint probability function of two or more discrete random variables. These probability tables have been previously studied
M.I. Ortego, J. J. Egozcue
doaj   +1 more source

Observed Range Maximum Likelihood Estimation [PDF]

open access: yes, 2011
The idea of maximizing the likelihood of the observed range for a set of jointly realized counts has been employed in a variety of contexts. The applicability of the MLE introduced in [1] has been extended to the general case of a multivariate sample ...
Markov, Plamen
core  

A Family of Quasisymmetry Models

open access: yes, 2014
We present a one-parameter family of models for square contingency tables that interpolates between the classical quasisymmetry model and its Pearsonian analogue. Algebraically, this corresponds to deformations of toric ideals associated with graphs. Our
Kateri, Maria   +2 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Symmetry of Square Contingency Tables Using Simplicial Geometry

open access: yesAustrian Journal of Statistics
Two-way contingency tables illustrate the relationship between two discrete variables. Their corresponding probability tables can be regarded as an element in a simplex.
Keita Nakamura   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Bayesian test of independence and conditional independence of two ordinal variables [PDF]

open access: yesJournal of Statistical Theory and Applications (JSTA), 2015
For analysis of contingency tables with large sample size, classical approaches using approximate methods have high power. However, when the sample size is small or some cells have frequencies less than 5, classical approaches are so conservative.
Zahra Saberi, Mojtab Ganjali
doaj   +1 more source

Sustainable energy development analysis: Energy Trilemma

open access: yesSustainable Technology and Entrepreneurship, 2022
Sustainable development is perceived as a socioeconomic system focused on meeting human needs while making long-term progress, with the end goal of ensuring well-being and improving quality of life.
Luisa Marti, Rosa Puertas
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

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