Results 51 to 60 of about 44,268 (251)

Printed Organic Thermoelectric Generators: Progress and Challenges Towards Efficient Energy Harvesting

open access: yesAdvanced Materials Technologies, EarlyView.
Printed organic thermoelectric generators (OTEGs) enable flexible and sustainable energy harvesting from low‐grade heat. This Perspective critically assesses recent advances in printable thermoelectric materials, 2D and 3D device architectures, and current performance limits of printed OTEGs.
Vijitha Ignatious   +5 more
wiley   +1 more source

QUANTIFICATION OF THE CATEGORIES OF DROSOPHILAS AND YEAST BY THE METHODS OF RECIPROCAL AVERAGES AND VARIANCE ANALYSIS

open access: yesPesquimat, 2014
A latent problem in two-dimensional contingency tables is to quantify the levels of categorical variables involved. In this paper we choose the nonlinear multivariate descriptive methods, Reciprocal averaging method and Variance Analysis method for ...
Doris Gómez Ticerán   +5 more
doaj   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang   +9 more
wiley   +1 more source

Simultaneous Analysis in S-PLUS: The SimultAn Package

open access: yesJournal of Statistical Software, 2011
In this paper we describe the SimultAn package dedicated to simultaneous analysis. Simultaneous analysis is a new factorial methodology developed for the joint treatment of a set of several data tables.
Amaya Zarraga, Beatriz Goitisolo
doaj  

Discovery of SKP2‐Recruiting PROTACs for Target Protein Degradation

open access: yesAdvanced Science, EarlyView.
Based on the SKP2‐targeting ligand SL1, we designed non‐covalent PROTACs by linking it with the BRD4 inhibitor JQ1 and the AR antagonist AL through a linker. These PROTACs successfully induced the ubiquitination of BRD4 and AR, followed by proteasome‐mediated degradation.
Guanjun Dong   +13 more
wiley   +1 more source

The Application of Canonical Correlation to Two-Dimensional Contingency Tables [PDF]

open access: yesTutorials in Quantitative Methods for Psychology, 2010
This paper re-introduces and demonstrates the use of Mickey’s (1970) canonical correlation method in analyzing large two-dimensional contingency tables. This method of analysis supplements the traditional analysis using the Pearson chi-square.
Alberto F. Restori   +2 more
doaj  

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

open access: yesAdvanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang   +7 more
wiley   +1 more source

Subsymmetry and asymmetry models for multiway square contingency tables with ordered categories

open access: yesOpen Mathematics, 2016
This paper suggests several models that describe the symmetry and asymmetry structure of each subdimension for the multiway square contingency table with ordered categories.
Aktaş Serpil
doaj   +1 more source

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

open access: yesAdvanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño   +5 more
wiley   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto   +20 more
wiley   +1 more source

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