Results 91 to 100 of about 1,938,271 (334)

Aura Continua [PDF]

open access: yesEpilepsia, 2005
Shashi S, Seshia, Richard S, McLachlan
openaire   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

A NOVEL CONCEPT OF THE BHATTACHARYYA’S THEOREM: √{-(x2+ y2)}= – √( x2+ y2 ) TO FIND THE SQUARE ROOT OF ANY NEGATIVE NUMBER INTRODUCING FERMAT’S LAST THEOREM IN REAL NUMBERS WITHOUT USING THE CONCEPT OF COMPLEX NUMBERS [PDF]

open access: yesJournal of Mechanics of Continua and Mathematical Sciences
In this paper, the author stated and proved Bhattacharyya’s Theorem: √{-(x2 + y2 )} = -√(x2 + y2). With the help of this theorem, the author finds the square root of any negative number introducing Fermat’s last theorem without using the concept of ...
Prabir Chandra Bhattacharyya
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Atriodic homogeneous continua [PDF]

open access: yesPacific Journal of Mathematics, 1984
The paper contains a classification of atriodic homogeneous continua. Every such continuum is either a solenoid, or a hereditarily indecomposable continuum, or it has a continuous decomposition to a solenoid with layers homeomorphic to the same hereditarily indecomposable homogeneous continuum.
openaire   +3 more sources

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

La cruda situación de la educación de adultos. Voces que se deben escuchar. Historias de vida contadas por sus protagonistas

open access: yesRevista Iberoamericana de Educación, 2007
En el presente documento se aborda la ardua problemática que vivencian algunos adultos de la provincia de San Luis que desertaron del sistema escolar hace ya varios años y desean culminar el trayecto escolar faltante. A los fines del trabajo se recurre a
Carmen María Belén Godino M.
doaj  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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