Results 101 to 110 of about 1,928,367 (285)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
EspergesiaEl presente estudio analiza el impacto de la Política Pública para la Prevención y Erradicación de la Violencia contra las Mujeres en la provincia de Manabí, se basa en su implementación desde la percepción ciudadana, el marco normativo y las acciones ...
Jeniffer Adriana Burgos Barreiro +1 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Extranjeras encarceladas. Olvidos y desigualdades
Hachetetepé, 2011 El objetivo de este artículo es dar algunas pinceladas, a manera de síntesis, de las discriminaciones principales que están padeciendo las mujeres extranjeras encarceladas en nuestro país, desde una perspectiva crítica, no androcéntrica y transformadora ...
Elisabet Almeda Samaranch, Dino Di Nella
doaj
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Saberes y Prácticas: Revista de Filosofía y Educación, 2018 La experiencia que aquí presento se propone describir las relaciones entre escuela y familias en instituciones primarias con jornada extendida insertas en contextos de pobreza urbana en la provincia de Río Negro tomando como eje de análisis las prácticas
María Soledad Fernandez
doaj +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Conmemoraciones sanmartinianas durante los gobiernos de la Revolución del 4 de junio de 1943
Antigua Matanza, 2017 Tanto los grupos que detentaron el poder, como los que luchan por alcanzarlo, utilizaron como herramienta al pasado y sobre todo a algunos referentes de ese pasado que puestos en el presente adquieren especiales significados.
Raúl ´Pomés
doaj