Results 131 to 140 of about 1,938,271 (334)

¿Qué hacer ante las desigualdades en la educación secundaria? Aportes de la experiencia latinoamericana

open access: yesRevista Iberoamericana de Educación, 2007
Jacinto, Claudia y Terigi, Flavia: “¿Qué hacer ante las desigualdades en la educación secundaria? Aportes de la experiencia latinoamericana. Editorial Santillana, Buenos Aires, 2007. La crisis, los fracasos, las deudas, los malestares de la educación,
Alfredo Ferrari
doaj  

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Las Actas y otros documentos del Cabildo de Santiago de Chile como fuentes para la reconstrucción de la minería colonial

open access: yesAntigua Matanza, 2018
Esta investigación busca lograr un primer avance sobre la minería (principalmente del oro, seguida en importancia por la de la plata) en la jurisdicción del Cabildo de Santiago del Nuevo Extremo (Santiago de Chile), durante el período que va entre el ...
Mauro Luis Pelozatto Reilly
doaj  

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