Results 101 to 110 of about 81,762 (303)
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
The influence of occupational rank on organizational commitment of faculty members
Management : Journal of Contemporary Management Issues, 2015 This study investigates the impact of rank on organizational commitment and explores the individual relationships between affective, normative and continuance commitment.
Vinita Sinha, Pooja Sharma
doaj
ORGANIZATIONAL COMMITMENT AS MEDIATOR VARIABLES ON THE RELATIONSHIP BETWEEN ORGANIZATIONAL JUSTICE AND TURNOVER INTENT [PDF]
, 2014 Current research conducted with two main concerns, first, to investigate the effect of distributive and procedural justice on turnover intent. And second, to examine the roles of affective, continuance and normative organizational commitment as the ...
Pareke, Fahrudin JS +2 more
core
FEBS Open Bio, EarlyView.Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen +6 more
wiley +1 more source
Jurnal Manajemen dan Wirausaha, 2020 The main objective of this paper was to examine relationships of generational diversity, personal attributes (i.e., work values; attitudes and behavior; and interpersonal skills) on organizational commitment among employees of corporate consultancies ...
Purani Verasamy +2 more
doaj +1 more source
Komitmen Antara Auditor Dan Klien: Anteseden Dan Konsekuensi [PDF]
, 2013 This research examines the antecendents and consequences of commitment in auditor andauditee relationship. Using mail survey to public company and client's of a local audit firmin Semarang, this research found client orientation is an important ...
Cahyonowati, N. (Nur)
core
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Leadership Styles and Effectiveness Among Sub-Saharan African Employees [PDF]
, 2018 This study sought to determine whether a significant relationship exists between dimensions of transactional and transformational leadership styles and leadership effectiveness within sub-Saharan Africa.
Fadare, Samuel
core +1 more source