Results 71 to 80 of about 623,226 (241)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Continuance theory and teacher education [PDF]

open access: yes, 2012
Continuance theory is usually related to the regular use of technology in the business/industry area. It attempts to explain why people either continue to use specific technologies in their work, or not.
Wright, Noeline
core   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Beyond the Three-Component Model of Organizational Commitment [PDF]

open access: yes
Adding to empirically based critique in the last 15 years, this paper offers a critical conceptual analysis of the three-component model of organizational commitment in order to arrive at a unequivocal grounding of the concept in standard attitudinal ...
Roe, R.A.   +2 more
core  

Middle managers’ role in organizational commitment and organizational citizenship behaviours [PDF]

open access: yes, 2015
“Any motivated behavior, either preparatory or consummatory, must be understood to be a channel through which many basic needs may be simultaneously expressed or satisfied.
Landa, Clive H.
core   +3 more sources

Pengaruh Dukungan Sosial dan Kepemimpinan Transformasional Terhadap Komitmen Organisasi dengan Mediator Motivasi Kerja

open access: yesJurnal Psikologi, 2015
The purpose of this research was to investigate the influence of social support and transformational leadership toward the three component model of organizational commitment (affective, continuance, and normative) with work motivation as a mediator ...
Miftahun Ni’mah Suseno, - Sugiyanto
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

The relationship between organizational commitment and intention to leave: A model of two components of continuance commitment

open access: yesManagement Letters/Cuadernos de Gestión, 2010
The aim of this article is to provide empirical evidence on two questions belonging to the research agenda of organizational commitment research: the possible existence of several facets of continuance commitment, and of non-linear relationships between ...
Jose M. Sallán   +3 more
doaj  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

PERANAN GOOD CORPORATE GOVERNANCE DALAM MEMPREDIKSI FINANCIAL DISTRESS

open access: yesMatrik, 2016
This study aims to find the effect of job involvement and organizational justice on three types of organizational commitment, which are affective, continuance and normative. This research was conducted in Pacto-Bali, using 70 employees as its respondents.
Diah Mentari Cahyani   +1 more
doaj   +1 more source

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