Results 121 to 130 of about 1,866,320 (298)

On the Ramanujan-Gollinitz-Gordon Continued Fraction

open access: yes, 2013
[[abstract]]We derive many new identities involving the Ramanujan-Göllnitz-Gordon continued fraction H(q). These include relations between H(q) and H(q n ) , which are established using modular equations of degree n. We also evaluate explicitly H(q) at q
Chan, Heng-Huat; Huang, Sen-Shan
core  

Continued Fraction Approximations

open access: yes, 2016
Any real number can be expanded in a continued fraction. Truncating the regular continued fraction after n terms gives a rational number. This Demonstration shows the differences between function values f(x) and regular continued fraction approximations ...
Trott, Michael
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

The Rogers-Ramanujan Continued Fraction

open access: yes, 2013
[[abstract]]A survey of many theorems on the Rogers–Ramanujan continued fraction is provided.
Berndt, Bruce C. ; Chan, Heng-Huat; Huang, Sen-Shan; Kang, Soon-Yi; Sohn, Jaebum; Son, Seung-Hwan
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

On simple circular sets of absolute convergence for branched continued fractions of the special form

open access: yesKarpatsʹkì Matematičnì Publìkacìï, 2012
The radii of the circles with center in origin of coordinates that are simple sets of absolute convergence for branched continued fractions of the special form have been investigated.
T.M. Antonova
doaj  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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