Results 91 to 100 of about 1,647,438 (306)

Relapse prevention for addictive behaviors

open access: yesSubstance Abuse Treatment, Prevention, and Policy, 2011
The Relapse Prevention (RP) model has been a mainstay of addictions theory and treatment since its introduction three decades ago. This paper provides an overview and update of RP for addictive behaviors with a focus on developments over the last decade (
George William H   +3 more
doaj   +1 more source

Improving the Quality of Elder Care: The Continuing Care Retirement Community [PDF]

open access: yes, 2002
Includes bibliographical references.By 2020, the segment of the population 65 and older will have increased by 42% to reach over one million persons and those 85 and older will number roughly 129,000.
Dunn, Katie   +2 more
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Effectiveness and feasibility of deprescribing of symptomatic medications in a Singapore rehabilitation hospital

open access: yesProceedings of Singapore Healthcare, 2019
Introduction: This study aims to determine the effectiveness, cost savings and feasibility of implementing a systematic process of deprescribing medications for symptomatic management, namely, acid suppressants, laxatives, analgesics and antiemetics for ...
Charissa Ann Jia Ming Ee   +3 more
doaj   +1 more source

NHS Continuing Healthcare funding: anomalous, irregular, and often baffling [PDF]

open access: yes, 2017
The boundary between health and social care continues to be a major issue, and is especially stark around long-term care and NHS continuing healthcare.
Henwood, Melanie
core  

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Lessons from Health Care Fraud Cases: Implications for Management of Health Care Entities [PDF]

open access: yes, 2013
Fraud has been a major issue all throughout the health care industry. There have been many cases around the world in relation to health care fraud. There are several laws now that do try to reduce the amount of healthcare fraud, but more changes could ...
Onofaro, Haley
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Application progress of continuous nursing based on Wechat platform in patients with acute mastitis (基于微信平台的延续护理在急性乳腺炎患者中的应用进展)

open access: yes中西医结合护理
Acute mastitis not only causes maternal discomfort, but also affects breastfeeding. This paper introduces the definition of continuous nursing and the application advantages of Wechat platform in the transitional care of acute mastitis.
FAN Dongpan (范东盼)   +1 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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