Results 121 to 130 of about 1,647,438 (306)
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
ObjectiveKnee osteoarthritis (KOA) is a degenerative joint condition, leading to disability and diminished quality of life. Molecular hydrogen has been proven to have antioxidant and anti-inflammatory properties, but few studies have investigated its ...
Chenhui Wang +9 more
doaj +1 more source
Resolving Chronic Care Needs Under and Acute Care Model: Implications in Discharge Planning for Long Term Care [PDF]
The University Archives has determined that this item is of continuing value to OSU's history.Presenter: Evelyn P. Mahairas, Ph.D., BCD, Program Director, ITTG (Interdisciplinary Team Training in Geriatrics), VA Medical Center, Coatesville, PA; Clinical ...
Mahairas, Evelyn P.
core
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Em Portugal surge, em 2006, a Rede Nacional de Cuidados Continuados Integrados - RNCCI, que procura proporcionar cuidados continuados às pessoas idosas e cidadãos com dependência. Neste contexto, onde os enfermeiros desempenham um papel preponderante, há
João Paulo de Almeida Tavares +1 more
doaj
Double Secret Protection: Bridging Federal and State Law To Protect Privacy Rights for Telemental and Mobile Health Users [PDF]
Mental health care in the United States is plagued by stigma, cost, and access issues that prevent many people from seeking and continuing treatment for mental health conditions. Emergent technology, however, may offer a solution.
Sherman, Josh
core +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source

