Results 121 to 130 of about 1,647,438 (306)

Continuity of Care [PDF]

open access: yesKorean Journal of Family Medicine, 2017
openaire   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Hydrogen-oxygen mixture inhalation as an adjunctive treatment to home-based exercise in older patients with knee osteoarthritis: an open-label, blinded-endpoint, randomized controlled trial

open access: yesFrontiers in Pharmacology
ObjectiveKnee osteoarthritis (KOA) is a degenerative joint condition, leading to disability and diminished quality of life. Molecular hydrogen has been proven to have antioxidant and anti-inflammatory properties, but few studies have investigated its ...
Chenhui Wang   +9 more
doaj   +1 more source

Resolving Chronic Care Needs Under and Acute Care Model: Implications in Discharge Planning for Long Term Care [PDF]

open access: yes, 1989
The University Archives has determined that this item is of continuing value to OSU's history.Presenter: Evelyn P. Mahairas, Ph.D., BCD, Program Director, ITTG (Interdisciplinary Team Training in Geriatrics), VA Medical Center, Coatesville, PA; Clinical ...
Mahairas, Evelyn P.
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Barreiras e soluções nos Cuidados Continuados a Pessoas Idosas: percepções de Enfermeiros(as) Barreras y soluciones en los Cuidados Continuos a Personas Ancianas: percepciones de Enfermeros(as) Barriers and solutions in Continuing Care for the Elderly: Nurses’ perceptions

open access: yesRevista de Enfermagem Referência, 2010
Em Portugal surge, em 2006, a Rede Nacional de Cuidados Continuados Integrados - RNCCI, que procura proporcionar cuidados continuados às pessoas idosas e cidadãos com dependência. Neste contexto, onde os enfermeiros desempenham um papel preponderante, há
João Paulo de Almeida Tavares   +1 more
doaj  

Double Secret Protection: Bridging Federal and State Law To Protect Privacy Rights for Telemental and Mobile Health Users [PDF]

open access: yes, 2018
Mental health care in the United States is plagued by stigma, cost, and access issues that prevent many people from seeking and continuing treatment for mental health conditions. Emergent technology, however, may offer a solution.
Sherman, Josh
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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