Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Huli yanjiu, 2018 Objective:To explore the influence of community continuing care intervention based on transtheoretical model on the quality of life of asthmatic patients.Methods:From January 2016 to January 2017,150 patients with asthma in the department of respiratory ...
Yin Hang
doaj
A holistic perspective on continuing care for substance use and dependence: Results and implications from an in-depth study of a Norwegian continuing care establishment. [PDF]
Nordisk Alkohol Nark, 2022 Høyland SA, Schuchert A, Mamen A.
europepmc +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Retracted: Clinical Efficacy and Psychological Impact of Omaha-Based Continuing Care for Prostate Cancer Patients. [PDF]
Comput Math Methods Med, 2023 Methods In Medicine CAM.
europepmc +1 more source
Towards the development of a resource allocation model for primary, continuing and community care in the health services - Volume 1 [PDF]
, 2010 This report proposes a resource allocation model for the Irish health services based on the principle that each Irish resident should be provided with access to health services funded from general taxation and in proportion to their need for those ...
Murrin, Celine +3 more
core +1 more source
FEBS Open Bio, EarlyView.KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
State Medicaid Agencies Prepare for Health Care Reform While Continuing to Face Challenges From the Recession [PDF]
, 2010 Summarizes findings from interviews with state Medicaid directors on the recession's impact on Medicaid; their role in and concerns about implementing healthcare reform, including insurance exchanges; and interest in innovations such as payment ...
core
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Retracted: Continuing Care Bundle in Elderly Patients with Rectal Cancer after Radical Resection with Permanent Stoma. [PDF]
Evid Based Complement Alternat Med, 2023 And Alternative Medicine EC.
europepmc +1 more source