Results 61 to 70 of about 1,700,006 (366)

Optimization of Pharmacotherapy Within the Framework of a Patient-oriented Approach in the Treatment of Hypertension in Multimorbidity Patients (Clinical Case and Literature Review)

Рациональная фармакотерапия в кардиологии, 2021
Arterial hypertension (AH) remains one of the main causes of disability and death worldwide, including in Russia. At the same time, the risks of coronary and cerebrovascular events increase in the presence of additional risk factors.
O. D. Ostroumova, I. A. Alyautdinova, S. N. Litvinova, A. V. Arablinskij, A. A. Kirichenko   +4 more
doaj   +1 more source

The Participants' viewpoint of continuing medical education courses [PDF]

, 2009
Background: Continuing education is one of the most effective methods to empower the employees for challengesthey face on their jobs. Dramatic advances in medicine, rapid cultural and social changes, increasing cost of healthcare, development of ...
Akhlaghi, Mahmood., khadivi, Reza., NASERI, M.   +2 more
core  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Evaluation of the Hemostatic Activity of Multicomponent Polymer Sponge Implants in An In Vitro Experiment

Неотложная медицинская помощь
BACKGROUND. The development of new samples of local hemostatic agents is an intensively developing area of the modern industrial biotechnology due to a high need of clinical bases for such products.
V. A. Lipatov, S. V. Lazarenko, D. A. Severinov, A. A. Denisov, O. V. Padalkina   +4 more
doaj   +1 more source

Applicability of the theory of planned behavior in explaining the general practitioners eLearning use in continuing medical education

BMC Medical Education, 2016
BackgroundGeneral practitioners (GP) update their knowledge and skills by participating in continuing medical education (CME) programs either in a traditional or an e-Learning format.
Arash Hadadgar, T. Changiz, I. Masiello, Z. Dehghani, Nahidossadat Mirshahzadeh, N. Zary   +5 more
semanticscholar   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Venereology at the Polyclinic: postgraduate medical education among General Practitioners in England, 1899–1914 [PDF]

, 2015
In 1899 the British Medical Journal enthusiastically announced that a new postgraduate teaching college was to open in London. The aim of the Medical Graduates’ College and Polyclinic (MGC) was to provide continuing education to general practitioners. It
Digby, Newman, Ross
core   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Key Strategies for Sustaining an Interprofessional Continuing Education Program

Journal of CME
Interprofessional teamwork is critical for effective care of patients in the current healthcare environment. Continuing Education providers are best positioned to teach healthcare professionals about interprofessional teamwork and the need to shift their
Steven Kawczak, Amanda Hall, Bethany Frampton, Molly Mooney, Anthony P. Fernandez   +4 more
doaj   +1 more source