Results 71 to 80 of about 184,985 (285)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

A Model for Predicting the Risk of Developing Drug-Induced Liver Injury During Therapy with Favipiravir

open access: yesАнтибиотики и Химиотерапия
Favipiravir is an antiviral drug that has become widely used for the etiotropic treatment of COVID-19. According to a number of studies, the incidence of adverse reactions during favipiravir therapy reaches 93%, and the most common adverse reaction is an
Yu. V. Shevchuk   +10 more
doaj   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Association between participation and compliance with Continuing Medical Education and care production by physicians: a cross-sectional study

open access: yesEinstein (São Paulo)
Objective Physician participation in Continuing Medical Education programs may be influenced by a number of factors. To evaluate the factors associated with compliance with the Continuing Medical Education requirements at a private hospital, we ...
Renato Melli Carrera   +9 more
doaj   +1 more source

Twelve tips for pedagogical production of learning objects for distance continuing medical education

open access: gold, 2021
Alessandra Tavares Francisco Fernandes   +3 more
openalex   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

Comparison of healthcare professionals’ motivations for using different online learning materials

open access: yesPediatric Investigation, 2019
Importance Online learning is increasingly prevalent throughout all stages of medical education. There is little published literature exploring what motivates healthcare professionals to engage with different types of e‐learning content.
Dennis Daniel, Traci Wolbrink
doaj   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

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