Results 161 to 170 of about 13,838,869 (315)

Cumulative equations for continuous time Chicago hyetograph method

open access: yesRBRH
The Chicago method is a classical method based on IDF curves for obtaining design hyetographs which present rainfall rates as continuous functions of time, one valid for times before peak and another for after peak.
André Luiz Lopes da Silveira
doaj   +1 more source

Continuous time and nonparametric modelling of U.S. interest rate models

open access: yes, 2003
In this paper we compare the forecasting performance of different models of interest rates using parametric and nonparametric estimation methods. In particular, we use three popular nonparametric methods, namely, artificial neural networks (ANN), k ...
Saltoglu, B., Nowman, K.B.
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Policy Gradient in Continuous Time.

open access: yesJ. Mach. Learn. Res., 2006
Policy search is a method for approximately solving an optimal control problem by performing a parametric optimization search in a given class of parameterized policies. In order to process a local optimization technique, such as a gradient method, we wish to evaluate the sensitivity of the performance measure with respect to the policy parameters, the
openaire   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Maximum Likelihood and Gaussian Estimation of Continuous Time Models in Finance

open access: yes
This paper overviews maximum likelihood and Gaussian methods of estimating continuous time models used in finance. Since the exact likelihood can be constructed only in special cases, much attention has been devoted to the development of methods designed
Jun Yu, Peter C. B. Phillips
core  

Under the Clouds of War

open access: yes, 1972
Consists of film clips of World War II events, including Mussolini\u27s invasion of Ethiopia and Hitler\u27s march into Austria.
Time-Life Video
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

On equilibrium prices in continuous time

open access: yes, 2008
Martins-da-Rocha VF, Riedel F. On equilibrium prices in continuous time. Working Papers. Institute of Mathematical Economics. Vol 397. Bielefeld: Universität Bielefeld; 2008.We combine general equilibrium theory and théorie générale of stochastic ...
Frank Riedel   +6 more
core  

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