Results 1 to 10 of about 5,206,546 (317)
3D molecular phenotyping of cleared human brain tissues with light-sheet fluorescence microscopy
An optimized clearing approach, named SHORT, applied to thick sections of human cortical tissue allows reconstruction of large portions of the tissues using light-sheet fluorescence microscopy, by performing multicolor immunostaining and multirounds.
Luca Pesce +11 more
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Assessing brain state and anesthesia level with two-photon calcium signals
Brain states, such as wake, sleep, or different depths of anesthesia are usually assessed using electrophysiological techniques, such as the local field potential (LFP) or the electroencephalogram (EEG), which are ideal signals for detecting activity ...
Núria Tort-Colet +5 more
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By using laser tweezers, the authors show that a single α-catenin molecule does not resist force on F-actin. However, clustering of multiple molecules and force applied toward F-actin pointed end engage a molecular switch in α-catenin, which unfolds and ...
C. Arbore +8 more
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Autofluorescence enhancement for label-free imaging of myelinated fibers in mammalian brains
Analyzing the structure of neuronal fibers with single axon resolution in large volumes is a challenge in connectomics. Different technologies try to address this goal; however, they are limited either by the ineffective labeling of the fibers or in the ...
Irene Costantini +11 more
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Optogenetics is an emerging method that uses light to manipulate electrical activity in excitable cells exploiting the interaction between light and light-sensitive depolarizing ion channels, such as channelrhodopsin-2 (ChR2).
Francesco Giardini +5 more
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A global perspective on western Mediterranean precipitation extremes
The Mediterranean region has been declared a climate change hotspot due, among other reasons, to an expected increase in the torrential rains that frequently affect this densely populated area.
Damián Insua-Costa +3 more
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Response Measurements on an Echinodome Subjected to Explosive Loading
Free field explosion experiments were carried out to determine the general characteristics of the pressure pulse generated by a detonator underwater. An echinodome – an axisymmetric shell structure of optimum form – was subjected to a shock wave from the
K.M.M. El-Deeb, R. Royles
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Fiber-Based SERS-Fluidic Polymeric Platforms for Improved Optical Analysis of Liquids
Downsizing surface-enhanced Raman spectroscopy (SERS) within microfluidic devices has opened interesting perspectives for the development of low-cost and portable (bio)sensors for the optical analysis of liquid samples. Despite the research efforts, SERS-
Caterina Credi +6 more
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Background Visually guided behaviors such as optomotor and optokinetic responses, phototaxis, and prey capture are crucial for survival in zebrafish and become apparent after just a few days of development.
Chiara Fornetto +3 more
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In this paper, we investigate the control of 4-D nonautonomous fractional-order uncertain model of a PI speed-regulated current-driven induction motor (FOIM) using a fractional-order adaptive sliding mode controller (FOASMC).
Karthikeyan Rajagopal +3 more
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