Results 1 to 10 of about 362,084 (118)
Frontiers in Cell and Developmental Biology, 2021 X-linked hypophosphatemia (XLH) is the most common form of genetic rickets. Mainly diagnosed during childhood because of growth retardation and deformities of the lower limbs, the disease affects adults with early enthesopathies and joint structural ...
Axelle Cauliez +16 more
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Genetically engineered mice for combinatorial cardiovascular optobiology
eLife, 2021 Optogenetic effectors and sensors provide a novel real-time window into complex physiological processes, enabling determination of molecular signaling processes within functioning cellular networks. However, the combination of these optical tools in mice
Frank K Lee +14 more
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Growth hormone treatment improves final height in children with X-linked hypophosphatemia
Orphanet Journal of Rare Diseases, 2022 Background/aim Despite optimal conventional treatment (oral phosphate supplements and active vitamin D analogs), about 40–50% of children with well-controlled X-linked hypophosphatemia (XLH) show linear growth failure, making them less likely to achieve ...
Julia André +8 more
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Frontiers in Cell and Developmental Biology, 2020 X-linked hypophosphatemia (XLH) is characterized by rickets and osteomalacia, caused by inactivating mutations in the Phosphate-regulating endopeptidase homolog X-linked (PHEX) gene.
Carole-Anne Faraji-Bellée +19 more
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Denoising two-photon calcium imaging data. [PDF]
PLoS ONE, 2011 Two-photon calcium imaging is now an important tool for in vivo imaging of biological systems. By enabling neuronal population imaging with subcellular resolution, this modality offers an approach for gaining a fundamental understanding of brain anatomy ...
Wasim Q Malik +3 more
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Recent Advances of Calcium Carbonate Nanoparticles for Biomedical Applications
Bioengineering, 2022 Calcium carbonate nanoparticles have been widely used in biomedicine due to their biocompatibility and biodegradability. Recently, calcium carbonate nanoparticles are largely integrated with imaging contrast and therapeutic agents for various imaging and
Pengxuan Zhao +4 more
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A hardware system for real-time decoding of in vivo calcium imaging data
eLife, 2023 Epifluorescence miniature microscopes (‘miniscopes’) are widely used for in vivo calcium imaging of neural population activity. Imaging data are typically collected during a behavioral task and stored for later offline analysis, but emerging techniques ...
Zhe Chen +9 more
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Mesoscale calcium imaging in vivo: evolution and contribution to developmental neuroscience
Frontiers in Neuroscience, 2023 Calcium imaging is commonly used to visualize neural activity in vivo. In particular, mesoscale calcium imaging provides large fields of view, allowing for the simultaneous interrogation of neuron ensembles across the neuraxis.
Teresa Guillamón-Vivancos +4 more
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Quantitative analysis of 1300-nm three-photon calcium imaging in the mouse brain
eLife, 2020 1300 nm three-photon calcium imaging has emerged as a useful technique to allow calcium imaging in deep brain regions. Application to large-scale neural activity imaging entails a careful balance between recording fidelity and perturbation to the sample.
Tianyu Wang +8 more
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Dendritic calcium signals in rhesus macaque motor cortex drive an optical brain-computer interface
Nature Communications, 2021 Surface two-photon imaging of the brain cannot access somatic calcium signals of neurons from deep layers of the macaque cortex. Here, the authors present an implant and imaging system for chronic motion-stabilized two-photon imaging of dendritic calcium
Eric M. Trautmann +20 more
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