Results 21 to 30 of about 359,534 (258)
Frontiers in Neural Circuits, 2021 Connected networks are a fundamental structure of neurobiology. Understanding these networks will help us elucidate the neural mechanisms of computation. Mathematically speaking these networks are “graphs”—structures containing objects that are connected.
Carl J. Nelson, Stephen Bonner
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F1000Research, 2021 Techniques for calcium imaging were first demonstrated in the mid-1970s, whilst tools to analyse these markers of cellular activity are still being developed and improved today.
Miranda Robbins +3 more
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A Novel Method to Quantify Calcium Response Pattern and Oscillation Using Fura2 and Acridine Orange
Journal of Pharmacological Sciences, 2004 To study calcium imaging data of cell populations that have various response patterns in peak amplitude and frequency of calcium oscillation in response to stimulation, comprehensive characterization based on statistical analysis of each response is ...
Mitsuhiro Morita +4 more
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Asante Calcium Green and Asante Calcium Red--novel calcium indicators for two-photon fluorescence lifetime imaging. [PDF]
PLoS ONE, 2014 For a comprehensive understanding of cellular processes and potential dysfunctions therein, an analysis of the ubiquitous intracellular second messenger calcium is of particular interest.
Karolina Jahn, Carsten Hille
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Fluorescent sensors for imaging of interstitial calcium [PDF]
Nature Communications, 2023 Abstract Calcium in interstitial fluids is central to systemic physiology and a crucial ion pool for entry into cells through numerous plasma membrane channels. Its study has been limited by the scarcity of methods that allow monitoring in tight inter-cell spaces of living tissues.
Ariel A. Valiente-Gabioud +8 more
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Calcium Sensor for Photoacoustic Imaging
Journal of the American Chemical Society, 2017 We introduce a selective and cell-permeable calcium sensor for photoacoustics (CaSPA), a versatile imaging technique that allows for fast volumetric mapping of photoabsorbing molecules with deep tissue penetration. To optimize for Ca2+-dependent photoacoustic signal changes, we synthesized a selective metallochromic sensor with high extinction ...
Sheryl Roberts +17 more
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Bio-Protocol, 2017 Fertilization calcium waves are a conserved trigger for animal development; however, genetic analysis of these waves has been limited due to the difficulty of imaging in vivo fertilization.
Jun Takayama +2 more
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High-Throughput Platform for Optoacoustic Probing of Genetically Encoded Calcium Ion Indicators
iScience, 2019 Summary: Functional optoacoustic (OA) imaging assisted with genetically encoded calcium ion indicators (GECIs) holds promise for imaging large-scale neuronal activity at depths and spatiotemporal resolutions not attainable with existing optical ...
Urs A.T. Hofmann +6 more
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Multiphoton Intravital Calcium Imaging [PDF]
Current Protocols in Cytometry, 2018 AbstractMultiphoton intravital calcium imaging is a powerful technique that enables high‐resolution longitudinal monitoring of cellular and subcellular activity hundreds of microns deep in the living organism. This unit addresses the application of 2‐photon microscopy to imaging of genetically encoded calcium indicators (GECIs) in the mouse brain.
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In vivo Calcium Imaging of Evoked Calcium Waves in the Embryonic Cortex [PDF]
Frontiers in Cellular Neuroscience, 2016 The dynamics of intracellular calcium fluxes are instrumental in the proliferation, differentiation, and migration of neuronal cells. Knowledge thus far of the relationship between these calcium changes and physiological processes in the developing brain has derived principally from ex vivo and in vitro experiments.
Mikhail eYuryev +9 more
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