Results 41 to 50 of about 1,903,568 (134)

A study on transfusion-transmitted infections and other complications amongst children with beta-thalassaemia major attending a tertiary care institution in Kolkata

Journal of Clinical and Scientific Research, 2023
Background: Chronic blood disorders such as beta-thalassaemia major require continuous blood transfusions, which results in complications such as transfusion-transmitted infections (TTIs), iron overload, skeletal deformities, endocrinal and cardiac and ...
Archi Chandra, Sarmila Mallik, Soma Chakrabarti, Nabanita Bhattacharyya   +3 more
doaj   +1 more source

Cytochrome c adsorption in a continuous flow system by using Cu(II)-chelated magnetic affinity particles

Bangladesh Journal of Medical Science, 2021
Background and methodology: In the current study magnetic poly(ethylene glycoldimethacrylate-N-methacryloyl-(L)-histidine methyl ester) poly(Egdma–Mah)) was used as ametal chelated affinity particles. Cu2+ ions loaded directly to MAH ligand of magnetic particlesfor the adsorption of cytochrome c (Cyt c) in a continuous flow system.
Akkaya, Birnur, Akkaya, Recep
openaire   +4 more sources

Lipid Peroxidation and Antioxidant Status in β-Thalassemic Patients: Effect of Iron Overload

Iraqi Journal of Pharmaceutical Sciences, 2017
To study the effect of iron overload due to continuous blood transfusions on peroxidation products, such as malondialdehyde (MDA) and peroxynitrite, with evaluation of some antioxidants like, glutathione (GSH), superoxide dismutase (SOD), vitamin A ...
Bassm N. Aziz, Mohammad A. Al-Kataan, Wasan K. Ali   +2 more
doaj   +3 more sources

Tailoring iron chelation by iron intake and serum ferritin: the prospective EPIC study of deferasirox in 1744 patients with transfusion-dependent anemias

Haematologica, 2010
Background Following a clinical evaluation of deferasirox (Exjade®) it was concluded that, in addition to baseline body iron burden, ongoing transfusional iron intake should be considered when selecting doses.
Maria Domenica Cappellini, John Porter, Amal El-Beshlawy, Chi-Kong Li, John F. Seymour, Mohsen Elalfy, Norbert Gattermann, Stéphane Giraudier, Jong-Wook Lee, Lee Lee Chan, Kai-Hsin Lin, Christian Rose, Ali Taher, Swee Lay Thein, Vip Viprakasit, Dany Habr, Gabor Domokos, Bernard Roubert, Antonis Kattamis   +18 more
doaj   +1 more source

Advances in iron chelation therapy: transitioning to a new oral formulation

, 2017
Iron overload is a concern for patients who require repeated red-blood-cell transfusions due to conditions such as sickle cell disease, thalassemia, or myelodysplastic syndromes.
Nirmish R Shah
core   +1 more source

Iron chelation therapy in transfusion-dependent thalassemia patients: current strategies and future directions [PDF]

, 2015
Antoine N Saliba, Afif R Harb, Ali T Taher Department of Internal Medicine, Division of Hematology/Oncology, American University of Beirut, Beirut, Lebanon Abstract: Transfusional iron overload is a major target in the care of patients with transfusion ...
Taher AT, Saliba AN, Harb AR, Saliba, Antoine N., Taher, Ali T., Harb, Afif R.   +5 more
core   +1 more source

Effect of Combined Hydroxyurea and Chelation Therapy in Reducing Serum Ferritin Level, Liver and Spleen Size in Transfusion Dependent Thalassaemia Major Patients.

Journal of Rawalpindi Medical College, 2019
Background: To compare hydroxyurea plus iron chelation therapy with iron chelation therapy alone in controlling iron overload in children with beta thalassaemia major.
Tatheer Zahra, Wajeeha Amber, Itrat Fatima   +2 more
doaj  

Chelation-Controlled Reduction:  Stereoselective Formation of syn-1,3-Diols and Synthesis of Compactin and Mevinolin Lactone

, 2016
Chelation-controlled reduction of chiral β-alkoxy ketones containing a competing β‘-oxygen functionality has been investigated. Various syn-1,3-diols were prepared conveniently by reduction of β-alkoxy ketones with LiI/LiAlH4 (syn:anti selectivity up to >
Hui Lei (2642707), Arun K. Ghosh (468637)   +1 more
core   +2 more sources

Endocrine complications

Thalassemia Reports, 2018
More than five decades ago, thalassemia major (TM) was fatal in the first decade of life. This poor prognosis changed since the survival rates started to increase progressively thanks to the implementation of continuous and significant improvement of ...
Vincenzo de Sanctis
doaj   +1 more source

Outcomes of chelation therapies.

, 2019
Outcomes of chelation therapies.
Brenda L. Gallie (249953), Nancy F. Olivieri (6407168), Amir Sabouhanian (6407171)   +2 more
core   +1 more source