Results 41 to 50 of about 2,120,442 (303)
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Defence TechnologyContinuous laser cleaning, while efficient for large-scale rust removal, often introduces excessive heat input, leading to substrate damage and inconsistent surface quality.
Jian Luo +3 more
doaj +1 more source
Hard surface biocontrol in hospitals using microbial-based cleaning products. [PDF]
PLoS ONE, 2014 Healthcare-Associated Infections (HAIs) are one of the most frequent complications occurring in healthcare facilities. Contaminated environmental surfaces provide an important potential source for transmission of many healthcare-associated pathogens ...
Alberta Vandini +8 more
doaj +1 more source
Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon +5 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Systematic digital framework for optimizing changeover cleaning in pharmaceutical industries
Cleaner Engineering and TechnologyA generalized and systematic framework for optimizing the changeover cleaning process in pharmaceutical manufacturing has been developed, with its application demonstrated in various scenarios to facilitate better decision-making regarding cleaning. This
Megha Das +2 more
doaj +1 more source
Analytics on Non-Normalized Data Sources: More Learning, Rather Than More Cleaning
IEEE Access, 2022 Data analysis is increasingly performed over data assembled from uncontrolled sources, facing inconsistency in knowledge-representation conventions. The typical practice is to create “clean” data for analysis, matching entities and merging ...
Alexis Cvetkov-Iliev +2 more
doaj +1 more source
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
Applied SciencesA new multi-scenario, low-cost, high-efficiency, medium-assisted continuous laser cleaning of corrosion layers was developed. By comparing the roughness and cleaning depth of rust layers cleaned under conditions of liquid-assisted, solid-assisted, and ...
Kunyu Cui +4 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu +7 more
wiley +1 more source